Central Laminated Keratotic Debris

On histologic examination the tumors are composed of an endophytic exophytic cup shaped squamous epidermal proliferation containing a crater like center filled with laminated keratotic material fig.

Central laminated keratotic debris.

Presents with pruritic hyperkeratotic and ulcerated nodules and papules with a central keratotic plug mostly located on extensor surface of upper and lower limbs and on the trunk. Dna polymerase chain reaction pcr and gene sequencing studies performed on the tissue of the microscopic slide and paraffin block for the recently identified ts associated. Electron microscopic studies of a follicular lesion showed extracellular viral particles suggestive of a polyomavirus within the central follicular keratotic debris. Keratin is a fibrous protein found in nails hair and the outer layer of skin.

Hypertrophy of the cornea. Right side contact us all pages. Other links at bottom. The lesions mainly occur on the scalp back and extensor surface of the legs and are asymmetrically distributed and hyperpigmented with central round or irregularly shaped keratotic plugs.

Actinic keratosis a sharply outlined wartlike or keratotic growth which may develop into a cutaneous horn and may become malignant. A recent study described two siblings who developed kd at 2 and 4 years of age and were examined at 7 and 10 years of age respectively. Nail disorders are often due to keratin debris spreading within the nail bed. Two pyogenic granulomas arising from the wall of an epidermoid cyst on the midback of a 62 year old white man are reported.

See atlas 3. Keratotic debris ending with. This is exuded from the invagination seen in the fully evolved form of the lesion. A mixed inflammatory infiltrate.

Multiple keratoacanthomas may be seen in muir torre syndrome associated with sebaceous neoplasms and carcinomas of internal organs. Called also senile or solar keratosis. Subsequent re epithelization from the adjacent epidermis covers this entire process from the base. And a thinned variably ulcerated epidermis.

Hypertrophy of the horny layer of the skin or any disease characterized by it. Histologically each pyogenic granuloma was a polypoid sessile nodule that showed well vascularized granulation tissue. Left side donate all pages. Keratosis ker ah to sis any horny growth such as a wart or callosity.

It usually occurs in the middle aged or elderly and is due to excessive exposure to the sun. Send feedback or suggest a word or term. Epidermolytic hyperkeratosis a hereditary autosomal dominant form of ichthyosis present at birth. The absence of hair structure and the presence of inflammatory debris within the invaginations were highly suggestive of kyrle s disease.